Gilbert syndrome with elevated liver enzymes!

Authors

  • Adari Mounica Mediciti Institute of Medical Sciences, Ghanpur, Telangana, India Author
  • A Vinitha Author
  • K Sumathi Author
  • Preethi S Author
  • Sudharshanraj C Author

DOI:

https://doi.org/10.18231/pjms.v.15.i.1.240-242

Keywords:

Gilbert's syndrome, UGT1A1 gene, Phenobarbitone, Hereditary benign hyperbilirubinemia, Stressors

Abstract

 

Gilbert syndrome is a benign autosomal recessive condition of defective bilirubin metabolism in the liver. This syndrome may manifest with recurrent episodes of jaundice due to reduced glucuronidation of bilirubin resulting in raised unconjugated bilirubin levels but normal levels of transaminases. It results from polymorphisms in the UGT1A1 gene responsible for the conjugation of bilirubin. Even though it is a benign condition, it is of clinical importance because the hyperbilirubinemia can be precipitated by certain conditions like puberty, stress, infections, and menses. The present case report involves a case of Gilbert syndrome that is unveiled by drug-induced hepatitis.

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Published

2025-03-13

How to Cite

Gilbert syndrome with elevated liver enzymes!. (2025). Panacea Journal of Medical Sciences, 15(1), 240-242. https://doi.org/10.18231/pjms.v.15.i.1.240-242

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