Clinicopathological profile of benign soft tissue tumors- A study of 256 cases

Abstract

  Introduction: Soft tissue tumors are heterogenous group of tumors with diverse histology and similar clinical and radiological features. Benign soft tissue tumors outnumber sarcomas by a wide margin. Aim and Objectives: To perform category-wise analysis of benign soft tissue tumors and correlate histopathological distribution with clinical parameters. Materials and Methods: This was a retrospective type of study carried out over a period of four and half years. Histopathological examination of all the excisional biopsies of benign soft tissue tumors was performed. The tumors were classified as per WHO classification of soft tissue tumors 2013. The data was represented in the form of frequency and percentage. Analysis of histopathological findings was performed followed by correlation of histopathological findings with clinical parameters. Results: A total of 256 benign soft tissue tumors were studied. These tumors were most commonly seen in fourth decade of life and were more common in males with male to female ratio of 1.15: 1. Trunk was the most common site followed by upper extremity. Adipocytic tumors (215 cases, 84%) were most common among all the tumors, followed by nerve sheath tumors (27 cases 10.5%) and vascular tumors (12 cases 4.7%). There was one case each of benign fibrous histiocytoma and glomus tumor. Conclusion: Adipocytic tumors form the bulk of benign soft tissue tumors. But there is a considerable variety among the remaining small proportion of these tumors. Most of these have peculiarities regarding the age, gender and site-wise distribution.