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- DOI 10.18231/pjms.v.15.i.2.465-469
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CrossMark
- Citation
Neutrophil-to-lymphocyte ratio (NLR) in the acute coronary syndrome patients presenting in the pre and post-COVID-19 era
- Author Details:
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Vikas Chaudhary
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Ashwani Kumar
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Kuldeep S Laller
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Amit Kumar *
Background: The inflammatory pathways play a key role in the pathogenesis of acute coronary syndrome and the severe forms of COVID-19 disease. Thus inflammation may play an interrelation between these two critical situations.
Materials and Methods: In this study, the records of the patients of ACS admitted to the coronary care unit, were analyzed retrospectively. The two groups had 200 patients each. The group-A was randomly taken from the pre-COVID period of July to December 2019 while group-B patients were taken from the COVID/post-COVID period of July 2021 to December 2021. The two groups were compared for the severity of inflammation, through the leukocyte ratios of NLR and d-NLR.
Results: The neutrophil percentage as well as the ANC were significantly higher, while the percentage of lymphocytes and ALC were significantly lower in the group-B patients compared to the group-A patients (p ˂ 0.05). The NLR (mean ±SD) was significantly higher in group-B compared to group-A patients (6.38±4.84 vs 5.34±4.37, p ˂ 0.05), while the d-NLR showed no significant difference. The NLR values were significantly higher in group-B compared to group-A, for patients of age ˂ 45 years (7.13±5.8 vs 4.3±2.73, p ˂ 0.05) and for patients presenting with ST-Elevation ACS (7.17±5.2 vs 5.54±4.22, p ˂ 0.005).
Conclusion: The degree of inflammation as indirectly measured by the ratios of NLR and d-NLR, was found to be higher in the ACS patients presenting in the COVID/post-COVID era when compared to those in the pre-COVID era.
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How to Cite This Article
Vancouver
Chaudhary V, Kumar A, Laller KS, Kumar A. Neutrophil-to-lymphocyte ratio (NLR) in the acute coronary syndrome patients presenting in the pre and post-COVID-19 era [Internet]. Panacea J Med Sci. 2025 [cited 2025 Oct 27];15(2):465-469. Available from: https://doi.org/10.18231/pjms.v.15.i.2.465-469
APA
Chaudhary, V., Kumar, A., Laller, K. S., Kumar, A. (2025). Neutrophil-to-lymphocyte ratio (NLR) in the acute coronary syndrome patients presenting in the pre and post-COVID-19 era. Panacea J Med Sci, 15(2), 465-469. https://doi.org/10.18231/pjms.v.15.i.2.465-469
MLA
Chaudhary, Vikas, Kumar, Ashwani, Laller, Kuldeep S, Kumar, Amit. "Neutrophil-to-lymphocyte ratio (NLR) in the acute coronary syndrome patients presenting in the pre and post-COVID-19 era." Panacea J Med Sci, vol. 15, no. 2, 2025, pp. 465-469. https://doi.org/10.18231/pjms.v.15.i.2.465-469
Chicago
Chaudhary, V., Kumar, A., Laller, K. S., Kumar, A.. "Neutrophil-to-lymphocyte ratio (NLR) in the acute coronary syndrome patients presenting in the pre and post-COVID-19 era." Panacea J Med Sci 15, no. 2 (2025): 465-469. https://doi.org/10.18231/pjms.v.15.i.2.465-469