Clinico-pathological correlation of Oral cavity lesions in North Indian population

Authors: Priyanka Bhat, Syed Mohd Faiz, Anuja Bhargava, Saurabh Srivastava, Rajeev Krishna Gupta, Nirupma Lal, Litika Verma, Prajwal Gupta, Sanya Siddiqui

DOI: 10.18231/j.pjms.10046.1759833949

Keywords: oral malignancies, submucous fibrosis, leukoplakia, premalignant, malignant lesions.

Abstract: Aim and objectives : To evaluate the histopathological profile of oral cavity lesions who underwent oral mucosal biopsies. Introduction: Oral lesions are one of the common occurrences in the lifetime of a human being. Association of demographic and clinical profile of patients with type of oral lesions will be helpful to identify and quantify the role of different risk factors associated with different types of oral lesions. The present study was planned to carry out an evaluation of histopathological profile of oral cavity lesions and to analyze their association with clinicodemographic features at a tertiary care centre in North India. Material and Methods: Records of oral cavity biopsies of patients attending ENT OPD were taken. Diagnosis of all biopsies were evaluated on the basis of histopathological findings and correlated with the clinical symptoms and demographic findings. Result: Out of 146 patients, Oral cavity lesions were found in 99 males and 47 females, commonly affected age group was 20-40 years. The most common site involved was found to be buccal mucosa followed by tongue. The most common diagnosis came out to be squamous cell carcinoma followed by Submucous fibrosis and Leukoplakia. Benign lesions were present in 35 patients, 56 patients with Premalignant and 55 patients with malignant lesions. Conclusion: Our study shows oral cavity lesions were more common in males of the age group 20-40 years and site being buccal mucosa. The premalignant lesions were more common. Squamous cell carcinoma was found to be the most common diagnosis among all the lesions of oral cavity.