Evaluation of various physiological parameters affecting the outcomes in patients underwent dialysis procedure

Nouman Saleem, Zikria Saleem, Syed Atif Raza, Maryam Qamar, Hamza Masood


The kidney plays a vital role in homeostatic function by regulating the salts/water balance in the body. Renal function is compromised due to various factors internal and external conditions such as diabetic nephropathy (8.3%), hypertension (HTN) (42.2%), diabetes and hypertension (22.9%), drugs, age, and immune-related. Dialysis is the only option for end-stage renal disease (ESRD) beside kidney transplantation. This retrospective study was based on the collection of data from the profiles of patients undergoing dialysis in order to find the variations in physiological parameters such as; hemoglobin (Hb), bilirubin, serum creatinine, urea level, and blood pressure(B.P) both pre- and post-dialysis. Patients had concomitant diseases; hepatitis B virus (8.3%), hepatitis C virus (42.2%), diabetes mellitus (29.4%) and HTN (78.9%). Blood pressure was higher than the standard about 6-9mmHg systolic pre-dialysis and 10mm Hg post-dialysis. Whereas, the diastolic B.P was lower about 5mmHg pre-dialysis while it was up to the standards after dialysis. The Hb levels were within range showing the minor variation of about 0.2-0.3g/dL. Serum creatinine levels were higher 7.1985±3.26930 to7.9761±2.46952 and BUN was also higher than normal with the mean difference of about 0.2-5mg/dL. In conclusion, the blood pressure, hemoglobin, serum creatinine and blood urea nitrogen decreases which were raised earlier to dialysis. The weight of patient also decreased after dialysis. However increased in body weight have been observed in patients with kidney disease accompanied with diabetes. These parameters must be properly controlled to improve the health outcomes.

Keywords: Pre-dialysis, Post-dialysis, Hypertension, Diabetes Mellitus, Nephropathy

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