A profile of acute kidney injury in Eastern India: A cross sectional study

Amitava Mazumdar, Sujata Mazumdar, Ujjal Kumar Chakravarty, Tushar Kanti Pakira, Somnath Maitra, Santa Subhra Chatterjee

Abstract


Introduction: AKI is an important cause of morbidity and mortality with mortality remaining unchanged in the last decade inspite of advances in treatment.It is classified as pre renal, renal and post renal categories
with overlap. The classification criterias are RIFLE, KDIGO and AKIN, based on which the present study has been conducted, as the new markers of AKI such as NGAL,IL 18 and KIM 1 are not sensitive and specific.
Aims and Objectives: The purpose of the study is to determine the aetiologies, clinical features, risk factors and comorbidities associated with AKI in a Tertiary Care Hospital. 
Materials and Methods: This prospective observational study was conducted in RKMSP with 60 indoor patients after taking consent and applying the inclusion and exclusion criteria.After taking history and performing clinical examination,laboratory investigations were done and detailed statistical analysis was performed to obtain the results.
Results: Study showed that with rise of age, AKI increased. Females were more commonly affected with sepsis being the commonest cause and DM is the commonest associated co morbidity.Most of the patients were in RISK stage according to RIFLE criteria and incidence of AKI was more or less similar, according to different classification systems.
Conclusion: The importance of the study lies in the fact that study of risk factors, aetiology, clinical features and co morbities associated with AKI will pave the path for larger studies so that the mortality and morbidity from AKI may be modified.

Keywords: AKI, RIFLE, AKIN, KDIGO.


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