A Prospective study for assessing the role and significance of haematological parameters in diabetes in Southern Odisha

Ritushri Samantaray, Atanu Kumar Bal, Subhasis Mishra

Abstract


Background: In the present situation globally, there is an increasing burden of diabetes mellitus in  the developing and developed countries alike. With an increase in the carbohydrates intake due to the consumption of junk and unhealthy food, the cases of diabetes mellitus are alarmingly increasing. Diabetes is not a single disease in itself. It has been estimated that nearly 59.2 million patients around the world suffer from diabetes mellitus.
Aim: To assess the role and significance of haematological parameters in diabetes in Southern Odisha
Materials and Methods: It was a prospective study carried out at the Department of Pathology at the MKCG Medical College Berhampur, Ganjam (Odisha). The study period was from March 2019 to August 2019. One hundred subjects were registered for the study, among which 50 of the patients were in the diabetic group, and the remaining 50 were in the non-diabetic group (Group 1). The diabetics were further divided into two groups diabetics with HbA1c <7 with 25 patients (Group 2) and Diabetics with HbA1c >7 with 25 patients (Group 3). There are chances that patients with very low haemoglobin may show erroneous HbA1c values. Thus, to overcome this, we measure HbA1c of every patiente twice using Sebia Capillary Flex-Piercing instrument to acertain the accuracy and reliability of the study. The biological reference range in both males and females for RBC count is 3.8-6.5 million/cu.mm, Hb is 11.5-17mg/ dl, Hematocrit is 37-54%, MCV is 80-100m3 , MCH IS 27-32 pg, MCHC is 32-36g/dl and RDW is 11-16%. All the patients who had hypo/hyperthyroidism, CKD, an inflammatory disorder, and congenital heart disease were excluded from the study.
Result: Most of the patients were aged between 41-60 years in group 1, group 2, and group 3. It was also evident from the above table that the number of female patients was more as compared to the number of males. Among different values of red blood cell parameters in group 1 and group 2, there was a statistically significant difference between the two groups with respect to RBC. Also, there was a statistically significant difference between the group 1 and group 3 with respect to Hb values. 
Conclusion: In light of the above results, it was evident that the poor control diabetic subjects face more complex diseases along with anaemia. Therefore, it is required that the patients must undertake regular haemoglobin level tests so that the glycemic index is under control.

Keywords: Hb, Diabetes Mellitus, Red Blood Cells.


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