Assessment of cardiovascular risk due to dyslipidemia by framingham score and using this information for early initiation of treatment of hypothyroidism and reducing the risk for cardiovascular events

Puneet Goyal, Ankit Meshram

Abstract


Materials and Methods : This study was planned and carried out in The Department of Medicine M.G.M. Medical College and M.Y. Hospital Indore, patients with subclinical Hypothyroidism not taking any treatment and patients of overt hypothyroidism not taking treatment coming to the OPD. Study Design: Observational Study.
Result: In normal subject, the mean Framingham score was 0.89 0.57%, while in subclinical hypothyroidism patients it was 1.78 1.4% mg/dL showing a higher mean Framingham score in subclinical hypothyroidism patients as compared to normal subjects and the difference was found to be statistically
significant (P<0.05). In normal subject, the mean Framingham score was 0.89 0.57%, while in overt hypothyroidism patients it was 3.31 2.82%. showing a higher mean Framingham score in overt hypothyroidism patients as compared to normal subjects and the difference came out to be statistically significant (P<0.05). In subclinical hypothyroidism, the mean Framingham score was 1.78 1.4%, while in overt hypothyroidism patients it was 3.31 2.82%., showing a higher mean Framingham score in overt hypothyroidism patients as compared to subclinical hypothyroidism and the difference came out to be statistically significant (P<0.05).
Conclusion: Overt and subclinical hypothyroidism both are associated with increased cardiovascular risk indicated by the higher values of Framingham risk in these patients as compared to normal controls. Mean Framingham risk was 3.31 2.82% in overt hypothyroidism patients, 1.78 1.4% in subclinical
hypothyroidism and 0.89 0.57% in normal controls all of which were statistically significant[P<0.05].

Keywords: Cardiovascular, Dyslipidemia, Hypothyroidism & Framingham, Score.


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