Dry eyes in patients with pseudoexfoliation –A descriptive study

A Sivaraja Gowthaman, Elfride Farokh Sanjana, Hannah Ranjee Prasanth


Introduction: Pseudoexfoliation syndrome is seen commonly above 60 years of age. It can lead to various complications such as poor dilatation of pupil, increased IOP and intraoperative complications such as zonular dehiscence or capsular rupture, vitreous loss and subluxation of intraocular lens. Pseudoexfoliative glaucoma is one of the common types of secondary open angle glaucoma. Pseudoexfoliation syndrome can also cause ocular surface disorders due to tear film instability. Hence this study was done to assess the prevalence of dry eyes in patients with pseudoexfoliation.
Materials and Methods: This was a descriptive study which involved 150 eyes with pseudoexfoliation syndrome. Tear secretion assessment was done using Schirmer’s test I. Then the tear film stability was evaluated using Tear break-up time(TBUT). Ocular surface damage was assessed using Fluorescein staining and Lissamine green staining.
Result: Schirmer’s test I, 144 eyes out of 150 eyes had Schirmer’s test value more than 15 mm (96%). 4 eyes (2.6%) had value between 10-15 mm .2 eyes (1.4%) had value between 5-10 mm. Six eyes with dry eye syndrome were identified by Schirmer’s test I. Tear breakup time was decreased in 3 eyes (between 7-9 seconds). Three eyes with dry eye syndrome were identified by TBUT test. Fluorescein staining was positive in one eye. Lissamine staining was positive in 2 eyes with score of 2 and 3. In this study of
pseudoexfoliation patients, there were 9 eyes(6%) with dry eye syndrome.
Conclusion: Early recognition of dry eye syndrome in patients with pseudoexfoliation syndrome can reduce ocular morbidity and prevent a significant compromise in their quality of life.

Full Text: